A rare case of giant cutaneous leiomyosarcoma: A case report [Turkderm-Turk Arch Dermatol Venereol]
Turkderm-Turk Arch Dermatol Venereol. 2015; 49(3): 226-228 | DOI: 10.4274/turkderm.58235  

A rare case of giant cutaneous leiomyosarcoma: A case report

Mehdi Iskandarli1, Bengü Gerçeker Türk1, Banu Yaman2, Can Ceylan1
1Department Of Dermatology And Venereology, Ege University Faculty Of Medicine, Izmir, Turkey
2Department Of Pathology, Ege University Faculty Of Medicine, Izmir, Turkey

Leiomyosarcoma (LMS) commonly evolving from smooth muscles of visceral organs like uterus, gastrointestinal system and has a worse prognosis due to its metastatic potential. LMS derived from smooth muscles of the skin, named superficial LMS, usually indolent and has a better prognosis. Especially LMS derived from pilar muscles usually restricted to the dermis and rarely metastasise. However, LMS developed from smooth muscles of subcutis, behaves more agressively and metastasing more oftenly. Here we report a case, in which patient consequently amputated and received chemotherapy due to giant superficial LMS on lower extremity which invaded underlying tissues like bone, tendons and joint and metastasized to the lung.

Keywords: Superficial leiomyosarcoma, subcutaneous leiomyosarcoma, metastasis

Nadir görülen dev kutanöz leiomyosarkom: Bir olgu sunumu

Mehdi Iskandarli1, Bengü Gerçeker Türk1, Banu Yaman2, Can Ceylan1
1Ege Univeristesi Tıp Fakültesi, Deri Ve Zührevi Hastalıkları Ana Bilim Dalı, İzmir, Türkiye
2Ege Univeristesi Tıp Fakültesi, Patoloji Ana Bilim Dalı, İzmir, Türkiye

Leiomyosarkomlar (LMS), kutanöz ya da visseral düz kas kökenli malign lezyonlardır. Uterus, gastrointestinal sistem gibi visseral düz kaslardan köken alan derin leiomyosarkomlar daha kötü prognoza sahiptir. Buna karşılık, derinin düz kaslarından köken alan yüzeyel leiomyosarkomlar daha iyi prognoz gösterir. Dermal kökenli LMS nadiren metastaz yaparken subkutan gelişim gösteren tipi daha agresif olup daha sık metastaz yapar. Bu sunumda alt ektremitede yüzeyel yerleşim gösteren, kemik ve eklem invazyonu yanısıra akciğer metastazı da yapan, diz altı ampütasyonu sonrasında kemoterapi uygulanan, dev bir leiomyosarkom olgusunu sunacağız.

Anahtar Kelimeler: Yüzeyel leiomyosarkoma, subkutan leiomyosarkoma, metastaz

Mehdi Iskandarli, Bengü Gerçeker Türk, Banu Yaman, Can Ceylan. A rare case of giant cutaneous leiomyosarcoma: A case report. Turkderm-Turk Arch Dermatol Venereol. 2015; 49(3): 226-228

Corresponding Author: Mehdi Iskandarli, Türkiye

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