Retrospective evaluation of patients with herpes zoster followed up in our department between 1999-2010

K���k�ak�r, O�uz; Alia�ao�lu, Cihangir; Turan, Hakan; Yan�k, Mehmet Emin; G�rlevik, Zehra; Acer, Ersoy; Albayrak, H�lya; G�nen, �bak

Retrospective evaluation of patients with herpes zoster followed up in our department between 1999-2010 [Turkderm-Turk Arch Dermatol Venereol]

Turkderm-Turk Arch Dermatol Venereol. 2012; 46(4): 186-190 | DOI: 10.4274/turkderm.93265

Retrospective evaluation of patients with herpes zoster followed up in our department between 1999-2010

O�uz K��k�ak�r¹, Cihangir Alia�ao�lu¹, Hakan Turan¹, Mehmet Emin Yan�k¹, Zehra G�rlevik¹, Ersoy Acer¹, H�lya Albayrak¹, �bak G�nen²
¹Department Of Dermatology, Duzce University Medical Faculty, D�zce
²Department Of Clinical Microbiology And Infectious Disease, Duzce University Medical Faculty, D�zce

Background and Design: Herpes zoster is a common viral disease of the nervous system. Although the annual incidence is 1.5�3/1000, this rate increases after 75 years of age. Seasonal factors are estimated to affect the incidence rate of the disease as well. The aim of this study was to investigate the clinical and demographic characteristics of patients diagnosed with herpes zoster and to explore the similarities and differences with other epidemiological studies from Turkey and the world.
Materials and Methods: We retrospectively reviewed the records of 312 patients diagnosed with herpes zoster and followed up in the D�zce University Medical Faculty Dermatology Department between January 1999 and December 2010.
Results: Herpes zoster patients comprised 0.56% of all patients who presented to our department. Their ages ranged from 6 months to 87 years (mean age: 49.6, median age: 53). The number of women and men was almost equal. Admissions were higher in January and December, with thoracic involvement being the most frequent one. Zoster was not a precursor of any occult malignancies. The most common associated systemic disease was cardiovascular disease. Pediatric cases comprised 7.4% of cases. Complications developed in 21.4% of patients. The most common complication was postherpetic neuralgia.
Discussion: There are only a few studies from our country on the epidemiology of herpes zoster. We observed that our findings were more or less similar to the findings of the literature data. However, unlike in other studies, in our study, the most common associated systemic disease was cardiovascular disease. It is thought that this is because this kind of chronic stressor weakens humoral and cellular immunity. We think that similar studies from different regions of our country are necessary to demonstrate the clinical and epidemiological characteristics of the disease more clearly.

Keywords: Epidemiology, herpes zoster

1999-2010 y�llar� aras�nda klini�imizde takip edilen herpes zoster olgular�n�n retrospektif de�erlendirilmesi

O�uz K��k�ak�r¹, Cihangir Alia�ao�lu¹, Hakan Turan¹, Mehmet Emin Yan�k¹, Zehra G�rlevik¹, Ersoy Acer¹, H�lya Albayrak¹, �bak G�nen²
¹D�zce �niversitesi T�p Fak�ltesi, Deri Ve Z�hrevi Hastal�klar Anabilim Dal�, D�zce,t�rkiye
²D�zce �niversitesi T�p Fak�ltesi, Klinik Mikrobiyoloji Ve Enfaksiyon Hastal�klar� Anabilim Dal�, D�zce,t�rkiye

Ama�: Herpes zoster sinir sisteminin yayg�n g�r�len viral bir hastal��d�r. Y�ll�k insidans� 1,5-3/1000 olmakla birlikte, 75 ya� �zerinde bu oran artmaktad�r. Mevsimsel fakt�rlerin hastal��n insidans�n� etkileyebilece�i d��n�lmektedir. Bu �al��man�n amac� herpes zoster tan�s� alm�� olan hastalar�n klinik, demografik �zelliklerinin incelenerek, T�rkiye ve d�nyadaki di�er epidemiyolojik �al��malarla benzerlik ve farkl�l�klar�n�n ortaya konmas�d�r.
Gere� ve Y�ntemler: �al��mam�zda D�zce �niversitesi T�p Fak�ltesi Deri ve Z�hrevi Hastal�klar Anabilim Dal�nda Ocak 1999-Aral�k 2010 tarihleri aras�nda herpes zoster tan�s� konulan 312 hastan�n dosyalar� retrospektif olarak de�erlendirildi.
Bulgular: Klini�imize ba�vuran t�m hastalar�n %0,56�s�n�n herpes zoster hastas� oldu�u g�zlenmi�tir. Hastalar�n ya�� 6 ay ile 87 ya� aras�nda de�i�mekteydi (ortalama 49,6; ortanca de�er 53). Kad�n ve erkek olgu say�s� hemen hemen e�itti. Ocak ve A�ustos aylar�nda ba�vuru say�s� daha fazla idi. En s�k torakal tutulum vard�. Herhangi bir gizli malinite �nc�s� de�ildi. Sistemik olarak en s�k kalp damar hastal�klar� ile birlikteli�i tespit edildi. Olgular�n %7,4��n�n �ocuk hasta oldu�u izlendi. Hastalar�n %21,4��nde komplikasyon saptand�. En s�k g�r�len komplikasyon postherpetik nevralji idi.
Sonu�: Herpes zoster epidemiyolojisiyle ilgili �lkemizde az say�da �al��ma oldu�u g�r�lmektedir. �al��ma sonu�lar�m�z� mevcut literat�r verileriyle k�yaslad��m�z zaman az veya �ok benzer bulgular�n oldu�unu g�zlemledik. Di�er �al��malardan farkl� olarak en s�k e�lik eden sistemik hastal�k kardiyovask�ler hastal�klard�. Bu durum bu t�r kronik stres yap�c� fakt�rlerin humoral ve h�cresel imm�niteyi zay�flatmas�na ba�lanm��t�r. �lkemizin farkl� b�lgelerinden benzer �al��malar�n hastal��n klinik ve epidemiyolojik �zelliklerinin daha net �ekilde ortaya ��kmas� i�in gerekli oldu�unu d��n�yoruz.

Anahtar Kelimeler: Epidemiyoloji, herpes zoster

O�uz K��k�ak�r, Cihangir Alia�ao�lu, Hakan Turan, Mehmet Emin Yan�k, Zehra G�rlevik, Ersoy Acer, H�lya Albayrak, �bak G�nen. Retrospective evaluation of patients with herpes zoster followed up in our department between 1999-2010. Turkderm-Turk Arch Dermatol Venereol. 2012; 46(4): 186-190

Corresponding Author: Hakan Turan, T�rkiye

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