Background and Design: The ongoing rampage of dermatophytic infection continues to challenge dermatologists with its varied presentations, sparing no age group. Thus, this study was undertaken to assess the clinical, demographic, and microbiological aspects of childhood tinea infection.
Materials and Methods: A descriptive, cross-sectional study was conducted in 200 consecutive pediatric patients (under 14 years of age) diagnosed with dermatophytosis between January 2019 and March 2020. All patients underwent detailed history, thorough clinical examination, microbiological confirmation with potassium hydroxide mount and fungal culture.
Results: The majority of the study population (44.5%) belonged to the 3 ≤9 years age group with a mean age of 6.1 ± 3.3 years, with an overall male predominance. More than one-third of the patients (39%) belonged to the ‘low’ socioeconomic stratum and lived in rural areas. Similar affliction among family members was recorded in 83.5%. Chronic and recurrent dermatophytosis was diagnosed in 9% of patients. The most common site involved was the trunk. Clinically, the most commonly diagnosed condition was tinea corporis (92%). More than half of the patients (53.5%) reported usage of prior topical steroid-laced creams. The most common fungus was Trichophyton mentagrophytes.
Conclusion: A substantial pediatric population is afflicted by the ongoing scourge of superficial dermatophytosis. Results from our study corroborate with the studies done by Indian investigators on adult patients suffering from dermatophytosis. Multicentric collaboration with added molecular studies assessment is needed to address this growing concern in the pediatric age group.

Background and Design: As YouTube becomes more popular as a source of health information, concerns about the reliability of its content are also increasing. While many studies have evaluated health-related content on YouTube, nail-related videos remain under-reviewed. This study aims to assess the engagement and quality of Turkish-language YouTube videos on nail health and disorders, focusing on their subject, content, creators, and sources of information.
Materials and Methods: A cross-sectional content analysis was conducted on 500 Turkish YouTube videos, collected using relevant keywords. Video data, including upload dates, duration, views, likes, and comments, were retrieved via a Python script using the YouTube Data API. Videos were categorized by uploader and person providing information in the video, and content quality was assessed using the Global Quality Scale (GQS). Descriptive statistics and non-parametric tests were used for data analysis.
Results: The most common video topics were ingrown toenail (39.0%), onychomycosis (31.8%), and nail health and care (9.4%), with the latter receiving the highest engagement in terms of views, likes, and comments. Although healthcare providers were the primary sources of information in 67% of the videos, independent non-healthcare content creators and patients attracted the most interaction. Healthcare professionals, particularly dermatologists, provided higher quality information in the videos than non-healthcare creators, yet these videos received less engagement. Videos containing herbal therapies and alternative medicine garnered the most attention but also had the lowest GQS scores.
Conclusion: Turkish-language YouTube content on nail health and disorders is primarily dominated by non-healthcare creators, who attract higher engagement despite lower content quality. A contrast exists between audience interactions and video quality. Patients seeking health information on YouTube should exercise caution to avoid being misinformed. Healthcare professionals should enhance their online presence by creating accurate and engaging content to ensure patients can access reliable information.

Background and Design: Inflammatory linear verrucous epidermal nevus (ILVEN) is a rare, chronic dermatosis characterized by linear erythematous scaly plaques following Blaschko’s lines. This study aims to comprehensively evaluate ILVEN cases, focusing on demographic, clinical, and histopathological features to improve understanding of its presentation and management.
Materials and Methods: This retrospective cross-sectional study included 28 patients diagnosed at our center with clinically and histopathologically confirmed ILVEN between 2011 and 2022. Data on patient demographics, age at lesion onset, duration before diagnosis, lesion location, histopathological findings, and treatment approaches were collected from hospital records and supplemented by patient interviews.
Results: Our study had a male predominance (63.4%), with a median age of lesion onset at 7.5 years and a median age of 14 years, indicating a prolonged delay in diagnosis. The mean duration from lesion onset to diagnosis was 9.86 years. Lesions were most frequently located on the lower extremities, following a Blaschkoid distribution, with 73.3% of patients reporting pruritus. Key histopathological findings included orthokeratosis with hypergranulosis (60.7%), parakeratosis overlying hypogranulosis (46.4%), and psoriasiform epidermal hyperplasia (46.4%). Topical corticosteroids were the primary treatment modality, while spontaneous regression was observed in 14.3% of untreated cases.
Conclusion: This study highlights the clinical and histopathological features of ILVEN, emphasizing the importance of early recognition in reducing diagnostic delays. Further research is warranted to enhance understanding of ILVEN’s clinical course and to optimize diagnostic and therapeutic strategies.

Congenital atrichia with papules is a rare inherited disorder characterized by the replacement of hair follicles with keratinous cysts, resulting in hair loss shortly after birth and papular lesions. It should be differentiated from other causes of congenital atrichia, such as vitamin D-dependent rickets, alopecia universalis, and ectodermal dysplasia, to avoid unnecessary administration of medications and to counsel parents regarding the benign but irreversible nature of the condition.

Xeroderma pigmentosum (XP) is a rare autosomal recessive genodermatosis caused by mutations in the DNA repair system, leading to impaired repair of ultraviolet (UV) radiation-induced damage. XP is classified into seven nucleotide excision repair-deficient types (XPA to XPG) and a variant type (XPV). Diagnosis can be made at a later age in the XPV subtype, where sunburn reactions are known to be less severe. In this case, a 33-year-old male patient with a history of freckling that began at age 10 and basal cell carcinoma and squamous cell carcinoma in the head and neck region over the past 5 years presented with a suspicious non-pigmented 6 mm nodular lesion in the left subauricular region. Pathological examination revealed a diagnosis of malignant melanoma (MM). Concurrent genetic analysis revealed a homozygous c.491-6T>G mutation in the POLH gene, confirming a diagnosis of XPV. The mild clinical features of XP in our patient made the XPV diagnosis challenging, and the atypical dermoscopic features of the lesion complicated the clinical diagnosis of MM. It is reported that the age of onset of malignant skin tumors in XPV patients is later than in other groups, and the frequency of MM is higher. This case highlights the frequent delay in diagnosis and the diagnostic challenges of skin tumors in XPV patients.

Frontal fibrosing alopecia (FFA) is a scarring alopecia that primarily affects postmenopausal women. Although its etiology remains unknown, familial cases suggest a genetic basis. In this case report, we present the findings of three sisters with familial FFA, aged 55, 60, and 62 years, from Türkiye. Genetic analysis revealed that all three sisters shared the human leukocyte antigen (HLA)-A*11: 01; B*35: 01; C*04: 01 haplotypes. Two sisters had HLA-DRB1*03: 01 and HLA-DQB1*02: 01, while the third had HLA-DRB1*01: 01; HLA-DQB1*05: 01. The shared HLA-A*11: 01, B*35: 01, and C*04: 01 haplotype has not been previously associated with familial FFA. This finding marks the first familial FFA report from Türkiye and suggests a new genetic susceptibility haplotype for FFA in the Turkish population. The variation in HLA-DRB1 and HLADQB1 alleles among the sisters indicates complex genetic influences on the familial FFA. Further research is required to determine the role of these genetic variations in disease progression and to identify potential therapeutic approaches.