Lichen Planus Pemphigoides Associated with Bisoprolol

�lknur, Turna; Akarsu, Sevgi; Canbaz Avc�, Ceylan; �ar�anbal�, Saim; Lebe, Banu; Fetil, Emel

Main Page

Contact

Lichen Planus Pemphigoides Associated with Bisoprolol [Turkderm-Turk Arch Dermatol Venereol]

Turkderm-Turk Arch Dermatol Venereol. 2012; 46(2): 101-103 | DOI: 10.4274/Turkderm.23540

Lichen Planus Pemphigoides Associated with Bisoprolol

Turna �lknur¹, Sevgi Akarsu¹, Ceylan Canbaz Avc�¹, Saim �ar�anbal�¹, Banu Lebe², Emel Fetil¹
¹Department Of Dermatology And Venereology, Dokuz Eylul University, �zmir, Turkey
²Department Of Pathology, Dokuz Eylul University, �zmir, Turkey

Lichen planus pemphigoides (LPP) is a disease characterized by tense bullae arising on lichen planus papules and on clinically uninvolved skin, lichenoid infiltration and subepidermal bulla in histopathology, and linear deposits of IgG and C3 along basal membrane zone on direct immunofluorescence. This rare bullous dermatosis is usually idiopathic. However, in a few cases in the literature, it has been reported to be induced by hepatitis B, malignancies, phototherapy and some medications such as ramipril, captopril, cinnarizine and simvastatin. We reported a 35-year-old woman with LPP possibly induced by bisoprolol.

Keywords: Beta blockers, bisoprolol, lichen planus pemphigoides, lichenoid drug eruption

Bisoprolol ile �li�kili Liken Planus Pemfigoides

Turna �lknur¹, Sevgi Akarsu¹, Ceylan Canbaz Avc�¹, Saim �ar�anbal�¹, Banu Lebe², Emel Fetil¹
¹Dokuz Eyl�l �niversitesi T�p Fak�ltesi, Deri Ve Z�hrevi Hastal�klar� Ana Bilim Dal�, �zmir, T�rkiye
²Dokuz Eyl�l �niversitesi T�p Fak�ltesi, Patoloji Ana Bilim Dal�, �zmir, T�rkiye

Liken planus pemfigoides (LPP) klinik olarak gerek liken planus lezyonlar� �zerinde gerekse tutulmam�� deri b�lgelerinde yerle�imli gergin b�ller ile karakterize iken, histopatolojik olarak likenoid infiltrasyon ve subepidermal b�l olu�umu yan�nda direkt imm�nofloresan incelemede bazal membran boyunca lineer Ig G ve C3 birikimi ile karakterize bir hastal�kt�r. Nadir g�r�len bu b�ll�z dermatoz genellikle idiyopatik olmakla birlikte literat�rde hepatit B, maliniteler, fototerapi ve ramipril, kaptopril, sinnarizin ve simvastatin gibi baz� ila�lar ile tetiklenen az say�da olgu bildirilmi�tir. Burada bisoprolol kullan�m� ile tetiklendi�i d��n�len LPP�li 35 ya��nda bir kad�n olgu sunulmaktad�r.

Anahtar Kelimeler: Beta blokerler, bisoprolol, liken planus pemfigoides, likenoid ila� erupsiyonu

Turna �lknur, Sevgi Akarsu, Ceylan Canbaz Avc�, Saim �ar�anbal�, Banu Lebe, Emel Fetil. Lichen Planus Pemphigoides Associated with Bisoprolol. Turkderm-Turk Arch Dermatol Venereol. 2012; 46(2): 101-103

Corresponding Author: Sevgi Akarsu, T�rkiye

TOOLS

Full Text PDF

Download citation

RIS

EndNote

BibTex

Medlars

Procite

Reference Manager

Share with email

Send email to author

Similar articles

PubMed

Google Scholar