Annular elastolytic giant cell granuloma:  Case report

Akt�rk, Aysun; Bilen, Nilg�n; Yavuz, Metin; Y�ld�z, K�r�at D.; K�ran, Rebiay

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Annular elastolytic giant cell granuloma: Case report [Turkderm-Turk Arch Dermatol Venereol]

Turkderm-Turk Arch Dermatol Venereol. 2007; 41(3): 101-104

Annular elastolytic giant cell granuloma: Case report

Aysun Akt�rk¹, Nilg�n Bilen¹, Metin Yavuz¹, K�r�at D. Y�ld�z², Rebiay K�ran¹
¹Kocaeli �niversitesi T�p Fak�ltesi Dermatoloji Anabilim Dal�, Kocaeli, Turkey
²Kocaeli �niversitesi T�p Fak�ltesi Patolojianabilim Dal�, Kocaeli, Turkey

Annuler elastolytic giant cell granuloma (AEGCG) is a rare dermatosis which is characterized by phagocytosis of elastic fibres in dermis histopathologically. It is seen mostly in women as annular plaques located in skin areas exposed to sunlight. Fifty-five year-old female patient, presented to our department with annular plaques that developed on her face. She was diagnosed as AEGCG based on her clinical appearance, histopathological and laboratory findings after exclusion of lupus vulgaris and sarcoidosis. A moderate response in lesions was observed after 9 month with chloroquine phosphate treatment. We have presented our case in order to emphasize the necessity for remembering AEGCG in the differantial diagnoses of granulomatous dermatoses representing itself with annular lesions.

Keywords: Annuler elastolytic giant cell granuloma, Granuloma annulare, Sarcoidosis

An�ler elastolitik dev h�creli gran�lom: Olgu sunumu

Aysun Akt�rk¹, Nilg�n Bilen¹, Metin Yavuz¹, K�r�at D. Y�ld�z², Rebiay K�ran¹
¹Kocaeli �niversitesi T�p Fak�ltesi Deri ve Z�hrevi Hastal�klar Anabilim Dal�, Kocaeli, T�rkiye
²Kocaeli �niversitesi T�p Fak�ltesi Patolojianabilim Dal�, Kocaeli, T�rkiye

An�ler elastolitik dev h�creli gran�lom histopatolojik olarak dermisteki elastik liflerin fagositozuyla karakterize, nadir bir dermatozdur. Genellikle kad�nlarda g�ne�e maruz kalan deri b�lgelerinde an�ler plaklarla kendini g�sterir. Ellibe� ya��nda kad�n hasta, y�z�nde ortaya ��kan an�ler plaklarla b�l�m�m�ze ba�vurdu. Klinik g�r�n�m, histopatolojik bulgular ve laboratuar bulgular� ile olguda lupus vulgaris ve sarkoidoz d��lanarak an�ler elastolitik dev h�creli gran�lom (AEDHG) tan�s� konuldu. Dokuz ay s�reyle klorokin fosfat tedavisi ile lezyonlarda orta d�zeyde gerileme sa�land�. AEDHG�un an�ler lezyonlarla kendini g�steren gran�lomatoz dermatozlar�n ay�r�c� tan�s�nda akla gelmesi gerekti�ini vurgulamak i�in olgumuzu sunuyoruz.

Anahtar Kelimeler: An�ler elastolitik dev h�creli gran�lom, gran�loma anulare, sarkoidoz

Aysun Akt�rk, Nilg�n Bilen, Metin Yavuz, K�r�at D. Y�ld�z, Rebiay K�ran. Annular elastolytic giant cell granuloma: Case report. Turkderm-Turk Arch Dermatol Venereol. 2007; 41(3): 101-104

Corresponding Author: Aysun Akt�rk, T�rkiye

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