Paraneoplastic pemphigus in a patient with B cell non-hodgkin lymphoma

Yazgano�lu, Kurtulu� Didem; Bavbek, Sevil; B�y�kbabani, Nesimi; Baykal, Can

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Paraneoplastic pemphigus in a patient with B cell non-hodgkin lymphoma [Turkderm-Turk Arch Dermatol Venereol]

Turkderm-Turk Arch Dermatol Venereol. 2007; 41(1): 25-27

Paraneoplastic pemphigus in a patient with B cell non-hodgkin lymphoma

Kurtulu� Didem Yazgano�lu¹, Sevil Bavbek², Nesimi B�y�kbabani³, Can Baykal¹
¹�stanbul �niversitesi �stanbul T�p Fak�ltesi Dermatoloji Anabilim Dal�, �stanbul, Turkey
²�stanbul �niversitesi �stanbul T�p Fak�ltesi Onkoloji Enstit�s� Anabilim Dal�, �stanbul, Turkey
³�stanbul �niversitesi �stanbul T�p Fak�ltesi Patoloji Anabilim Dal�, �stanbul, Turkey

Paraneoplastic pemphigus (PNP) is a rare type of pemphigus which is seen in association with lymphoproliferative diseases, most commonly with non-Hodgkin's lymphoma and several other malignities. The disease presents with severe mucosal involvement, polymorphous skin eruption and respiratory problems. It has its own histopathologic features and immunfluorescence findings unlike the other types and has a poor prognosis. In this report, we describe a patient who developed PNP in two years after the diagnosis of B cell non-Hodgkin lymphoma.

Keywords: Paraneoplastic pemphigus, pemphigus, lymphoma

B h�creli hodgkin-d�� lenfoma seyrinde ortaya ��kan paraneoplastik pemfigus

Kurtulu� Didem Yazgano�lu¹, Sevil Bavbek², Nesimi B�y�kbabani³, Can Baykal¹
¹�stanbul �niversitesi �stanbul T�p Fak�ltesi Deri ve Z�hrevi Hastal�klar Anabilim Dal�, �stanbul, T�rkiye
²�stanbul �niversitesi �stanbul T�p Fak�ltesi Onkoloji Enstit�s� Anabilim Dal�, �stanbul, T�rkiye
³�stanbul �niversitesi �stanbul T�p Fak�ltesi Patoloji Anabilim Dal�, �stanbul, T�rkiye

Paraneoplastik pemfigus (PNP), ba�l�ca Hodgkin-d�� lenfomalar olmak �zere lenfoproliferatif hastal�klar�n ve �e�itli malinitelerin e�lik edebildi�i, klinik olarak �iddetli mukozal tutulum, polimorf deri lezyonlar� ve s�k solunum sorunlar�yla ortaya ��kan nadir bir pemfigus tipidir. Di�er pemfigus tiplerinden farkl� olarak kendine �zg� histopatolojik ve imm�nfloresan bulgular� olup, k�t� prognozludur. Bu yaz�da B h�creli Hodgkin d�� lenfoma tan�s� konduktan iki y�l sonra PNP tablosu geli�en bir olgu sunulmaktad�r.

Anahtar Kelimeler: Paraneoplastik pemfigus, pemfigus, lenfoma

Kurtulu� Didem Yazgano�lu, Sevil Bavbek, Nesimi B�y�kbabani, Can Baykal. Paraneoplastic pemphigus in a patient with B cell non-hodgkin lymphoma. Turkderm-Turk Arch Dermatol Venereol. 2007; 41(1): 25-27

Corresponding Author: Kurtulu� Didem Yazgano�lu, T�rkiye

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