Infantile Hemangioma

Ersoy Evans, Sibel

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Infantile Hemangioma [Turkderm-Turk Arch Dermatol Venereol]

Turkderm-Turk Arch Dermatol Venereol. 2011; 45(2): 133-137 | DOI: 10.4274/turkderm.45.s23

Infantile Hemangioma

Sibel Ersoy Evans
Hacettepe �niversitesi T�p Fak�ltesi, Deri ve Z�hrevi Hastal�klar Anabilim Dal�, Ankara

Infantile hemangioma (IH) is the most common benign tumor of infantile period. It appears few weeks after birth, grows rapidly in the first 4-6 months. Subsequently, growth stops and involution period which lasts about few years starts. It is more common in girls, premature infants, birthweight < 1500 gr, multiple gestations and Caucasians. Pathogenesis is not clearly known, however role of fetal hypoxic stres is considered. IH is a self-resolving benign lesion, yet in some localisations it may threaten organ function. Periorbital IH may cause ambylopia, astigmatism and strabismus. IH localised to beard area can lead to airway obstruction. Large facial IH can be a component of PHACE syndrome. Midline lumbosacral IH can be associated with spinal dysraphism. Other complications of IH include ulceration, heart failure, hypothyroidism, cosmetic dysfiguration. Treatment is indicated in ulcerated lesions, life/function threatening situations and lesions that can cause cosmetic nuissance. Corticosteroids, propranolol, interferon, vincristin, laser and surgery are used for this purpose.

Keywords: infantile hemangioma, vascular lesions, vascular tumors

�nfantil Hemanjiyomlar

Sibel Ersoy Evans
Hacettepe �niversitesi T�p Fak�ltesi, Deri Ve Z�hrevi Hastal�klar Anabilim Dal�, Ankara

�nfantil hemanjiyomlar (�H), infantil d�nemde en s�k g�r�len benign t�m�rlerdir. Do�umdan birka� hafta sonra ortaya ��kar, ilk 4-6 ay h�zl� b�y�rler. Daha sonra b�y�me durur ve birka� y�l s�ren invol�syon evresi ba�lar. K�zlarda, premat�relerde, do�um a��rl�� <1500 gr olanlarda, �oklu gebeliklerde ve beyaz �rkta daha s�k g�r�l�r. Patogenezi tam olarak bilinememekle birlikte f�tal hipoksik stresin rol� olabilece�i d��n�lmektedir. �H kendili�inden gerileyen iyi seyirli bir t�m�rd�r, ancak baz� lokalizasyonlarda organ fonksiyonunu tehdit edebilir. Periorbital �H�ler ambilopi, astigmat ve �a��l��a neden olabilir. Sakal b�lgesine yerle�en �H�ler havayolu obstr�ksiyonuna yol a�abilir. Y�zde yerle�im g�steren b�y�k �H�ler PHACE sendromu�nun bir par�as� olabilir. Orta hatta yerle�en lumbosakral �H�ler spinal disrafizm ile birlikte g�r�lebilir. �H�lerin di�er komplikasyonlar� �lserasyon, kalp yetmezli�i, hipotiroidi, kozmetik disfig�rasyondur. Tedavi �lsere, ya da hayat�/organ� tehdit eden durumlarda ve kozmetik �ekil bozuklu�u yaratabilecek lezyonlarda endikedir. Bu ama�la kortikosteroidler, propranolol, interferon, vinkristin, lazer ve cerrahi kullan�labilir.

Anahtar Kelimeler: infantil hemanjiyom, vask�ler lezyonlar, vask�ler t�m�rler

Sibel Ersoy Evans. Infantile Hemangioma. Turkderm-Turk Arch Dermatol Venereol. 2011; 45(2): 133-137

Corresponding Author: Sibel Ersoy Evans

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