Vitiligo related to autoimm�ne polyglandular syndrome:  Type 3B-3C

Do�an Sabuncuo�lu, Ye�im; Ya�ar, �irin; Ya�ar, B�lent; A�iran Serdar, Zehra

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Vitiligo related to autoimm�ne polyglandular syndrome: Type 3B-3C [Turkderm-Turk Arch Dermatol Venereol]

Turkderm-Turk Arch Dermatol Venereol. 2013; 47(3): 183-186 | DOI: 10.4274/turkderm.90692

Vitiligo related to autoimm�ne polyglandular syndrome: Type 3B-3C

Ye�im Do�an Sabuncuo�lu¹, �irin Ya�ar¹, B�lent Ya�ar², Zehra A�iran Serdar¹
¹Department of Dermatology, Haydarpa�a Numune Training and Research Hospital, Istanbul
²Department Of Gastroenterology, Caml�ca Erdem Hospital,�sk�dar, �stanbul

Vitiligo is an acquired hypomelanotic disorder characterized by depigmented macules resulting from the loss of functional melanocytes. The precise pathogenesis is not yet fully understood but there is evidence suggesting it is caused by a combination of autoimmune, genetic (APS), and neurohumoral factors. APS has a rare incidence; its four subtypes are accompanied by multiple endocrine deficiencies.
We report a case of APS-3B-3C in 32-year-old man with generalized autoimmune thyroiditis vitiligo and autoimmune gastritis.

Keywords: vitiligo, autoimmune polyglandular syndrome, autoimmune thyroiditis, autoimmune gastritis

Vitiligo ile ili�kili otoimm�n poligland�ler sendrom: T�P 3B+C

Ye�im Do�an Sabuncuo�lu¹, �irin Ya�ar¹, B�lent Ya�ar², Zehra A�iran Serdar¹
¹Haydarpa�a Numune E�itim Ve Ara�t�rma Hastanesi Deri ve Z�hrevi Hastal�klar B�l�m�, Kad�k�y, �stanbul
²�aml�ca Erdem Hastanesi Gastroenteroloji B�l�m�, �sk�dar, �stanbul

Vitiligo fonksiyonel melanositlerin kayb�na ba�l� depigmente mak�llerden olu�an kazan�lm�� hipomelanotik bir hastal�kt�r. Patogenezi tam anla��lamam�� olmakla birlikte bulgular, otoimm�n, genetik ve n�rohumoral fakt�rlerin kombinasyonu sonucu olu�tu�unu d��nd�rtmektedir. Otoimm�n poligland�ler sendrom(OPS) multipl endokrin organ yetmezli�i ile giden nadir bir hastal�k olup 4 alt tipi bulunmaktad�r.
Burada otoimm�n tiroidit, vitiligo ve otoimm�n gastritin bir arada oldu�u OPS-3B+C olarak de�erlendirilen 32 ya��ndaki bir erkek olgu bildirilmi�tir.

Anahtar Kelimeler: vitiligo, otoimm�n poliglanduler sendrom, otoimm�n tiroidit, otoimm�n gastrit

Ye�im Do�an Sabuncuo�lu, �irin Ya�ar, B�lent Ya�ar, Zehra A�iran Serdar. Vitiligo related to autoimm�ne polyglandular syndrome: Type 3B-3C. Turkderm-Turk Arch Dermatol Venereol. 2013; 47(3): 183-186

Corresponding Author: Ye�im Do�an Sabuncuo�lu, T�rkiye

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