Turkderm-Turk Arch Dermatol Venereol. 2020; 54(1): 25-28 | DOI: 10.4274/turkderm.galenos.2019.22567

Giant variant of acquired perforating dermatosis in a patient with diabetes mellitus

Sinan Özçelik¹, Yusuf Doðan¹, Arzu Kýlýç¹, Banu Lebe^2
1Balýkesir University Faculty of Medicine, Department of Dermatology, Balýkesir, Turkey
²Dokuz Eylül University Faculty of Medicine, Department of Pathology, Ýzmir, Turkey

Perforating dermatoses are a group of diseases characterized by transepidermal elimination of dermal components such as collagen, elastin and fibrin. Perforating dermatoses primarily include four main forms: reactive perforating collagenosis, elastosis perforans serpiginosa, perforating folliculitis and acquired perforating dermatosis. There is limited data about perforating dermatoses in the literature. Because of their rare appearance, they can be easily misdiagnosed. Acquired perforating dermatosis is a systemic disease such as diabetes and chronic renal failure; and it should be considered in case of pruritic papulonodules and giant plaques with central crater in a patient. In addition to the treatment of underlying disease in the first stage; narrow band ultraviolet B (nbUVB) is evaluated to be effective in these cases. Based on its rare occasions, we submit a giant variant of acquired perforating dermatosis with a collagen fiber predominant elimination pattern, which is treated with nbUVB.

Keywords: Perforating dermatosis, acquired perforating dermatosis, acquired reactive perforating collagenosis, phototherapy, giant variant

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Diabetes mellituslu bir olguda edinsel perforan dermatozun dev varyantý

Sinan Özçelik¹, Yusuf Doðan¹, Arzu Kýlýç¹, Banu Lebe^2
1Balýkesir Üniversitesi Týp Fakültesi, Deri ve Zührevi Hastalýklar Ana Bilim Dalý, Balýkesir
²Dokuz Eylül Üniversitesi, Patoloji Ana Bilim Dalý, Ýzmir

Perforan dermatozlar, kollajen, elastin, fibrin gibi dermal bileþenlerin transepidermal eliminasyonu ile karakterize bir grup hastalýktýr. Perforan dermatozlar primer olarak reaktif perforan kollajenöz, elastozis perforans serpiginoza, perforan folikülit ve edinsel perforan dermatoz olmak üzere dört ana hastalýk formunu kapsar. Perforan dermatozlarla ilgili literatürde az sayýda bilgi mevcuttur. Nadir görülmelerinden ötürü kolaylýkla dikkatten kaçabilmektedirler. Edinsel perforan dermatoz, özellikle diyabet, kronik böbrek yetmezliði gibi sistemik bir hastalýðý olup kaþýntýlý papülonodülleri, merkezi kraterli dev plaklarý olan hastalarda akla gelmelidir. Bu hastalarda öncelikli olarak alta yatan hastalýðýn tedavisine ek olarak dar bant Ultraviyole B’nin (dbUVB) etkili olabildiðini düþünmekteyiz. Biz de oldukça nadir görülmesi nedeniyle, dbUVB ile tedavi ettiðimiz, kollajen lif eliminasyon paterninin hakim olduðu dev lezyonlu bir edinsel perforan dermatoz olgusunu sunduk.

Anahtar Kelimeler: Perforan dermatoz, edinsel perforan dermatoz, akkiz reaktif perforan kollajenozis, fototerapi, dev varyant

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