Psoriasis and metabolic syndrome

Background and Design: Psoriasis is a chronic, inflammatory disease that occurs with poligenic and other triggering factors. Psoriasis which is accepted as a systemic disease has been verified to be associated with other diseases. Cardiovascular diseases, hepatosteatosis, obesity, diabetes mellitus, hypertension and hyperlipidemia are the ones that are the most significant.
Material and Method: In thýs study fasting blood glucose, serum lipid levels (total cholesterol, HDL cholesterol, triglyceride), basal insulin levels, insulin resistances and body mass indexes, cigarette and alcohol habits of 50 adult patients are compared with the age and gender matched 50 nonpsoriatic controls.
Conclusion: In our study, methabolic syndrome and its components diabetes mellitus, obesity, hypertension, dyslipidemia are found to be in higher rates in psoriatic group compared to nonpsoriatics.

Psoriasis ve metabolik sendrom

Amaç: Psoriazis, poligenik faktörler ve tetikleyici etkenler zemininde ortaya çýkan kronik, inflamatuar bir deri hastalýðýdýr. Günümüzde sistemik bir hastalýk olarak kabul gören psoriazisin baþka hastalýklarla da iliþkisi kanýtlanmýþtýr. Kardiyovasküler hastalýklar, karaciðer yaðlanmasý, obezite, diyabetes mellitus, hipertansiyon ve hiperlipidemi bu hastalýklarýn baþlýcalarýdýr.
Gereç ve Yöntem: Bu çalýþmada 50 yetiþkin psoriazis olgusunun açlýk kan glukozlarý, serum lipid deðerleri (total kolesterol, HDL kolesterol, LDL kolesterol, trigliserid), bazal insülin deðerleri, insülin dirençleri ve vücut kitle indeksleri, sigara ve alkol alýþkanlýklarý, yaþ – cinsiyet eþleþtirmeli 50 non-psoriatik kontrol olgu grubu ile karþýlaþtýrýlmýþtýr.
Sonuç: Çalýþmamýzda psoriazis olgularýnda metabolik sendrom ve komponentleri olan diyabetes mellitus, obezite, hipertansiyon, dislipidemi kontrol grubuna kýyasla daha yüksek oranda saptanmýþtýr.