Turkderm-Turk Arch Dermatol Venereol. 2015; 49(3): 226-228 | DOI: 10.4274/turkderm.58235

A rare case of giant cutaneous leiomyosarcoma: A case report

Mehdi Iskandarli¹, Bengü Gerçeker Türk¹, Banu Yaman², Can Ceylan^1
1Department Of Dermatology And Venereology, Ege University Faculty Of Medicine, Izmir, Turkey
²Department Of Pathology, Ege University Faculty Of Medicine, Izmir, Turkey

Leiomyosarcoma (LMS) commonly evolving from smooth muscles of visceral organs like uterus, gastrointestinal system and has a worse prognosis due to its metastatic potential. LMS derived from smooth muscles of the skin, named superficial LMS, usually indolent and has a better prognosis. Especially LMS derived from pilar muscles usually restricted to the dermis and rarely metastasise. However, LMS developed from smooth muscles of subcutis, behaves more agressively and metastasing more oftenly. Here we report a case, in which patient consequently amputated and received chemotherapy due to giant superficial LMS on lower extremity which invaded underlying tissues like bone, tendons and joint and metastasized to the lung.

Keywords: Superficial leiomyosarcoma, subcutaneous leiomyosarcoma, metastasis

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Nadir görülen dev kutanöz leiomyosarkom: Bir olgu sunumu

Mehdi Iskandarli¹, Bengü Gerçeker Türk¹, Banu Yaman², Can Ceylan^1
1Ege Univeristesi Týp Fakültesi, Deri Ve Zührevi Hastalýklarý Ana Bilim Dalý, Ýzmir, Türkiye
²Ege Univeristesi Týp Fakültesi, Patoloji Ana Bilim Dalý, Ýzmir, Türkiye

Leiomyosarkomlar (LMS), kutanöz ya da visseral düz kas kökenli malign lezyonlardýr. Uterus, gastrointestinal sistem gibi visseral düz kaslardan köken alan derin leiomyosarkomlar daha kötü prognoza sahiptir. Buna karþýlýk, derinin düz kaslarýndan köken alan yüzeyel leiomyosarkomlar daha iyi prognoz gösterir. Dermal kökenli LMS nadiren metastaz yaparken subkutan geliþim gösteren tipi daha agresif olup daha sýk metastaz yapar. Bu sunumda alt ektremitede yüzeyel yerleþim gösteren, kemik ve eklem invazyonu yanýsýra akciðer metastazý da yapan, diz altý ampütasyonu sonrasýnda kemoterapi uygulanan, dev bir leiomyosarkom olgusunu sunacaðýz.

Anahtar Kelimeler: Yüzeyel leiomyosarkoma, subkutan leiomyosarkoma, metastaz

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