Turkderm-Turk Arch Dermatol Venereol. 2008; 42(3): 97-99

A case of porokeratosis showing different clinical patterns of the disease with anogenital involvement

Özlem Karabudak¹, Bilal Doðan¹, Aptullah Haholu², Yavuz Harmanyeri^1
1Gata Haydarpaþa Teaching Hospital Department Of Dermatology, Istanbul, Turkey
²Gata Haydarpaþa Teaching Hospital Department Of Pathology,ýstanbul,turkey

Porokeratosis (PK) is a group of cutaneous entities characterized by marginate scaling lesions, histologically showing a column of parakeratotic keratinocytes (cornoid lamella). Various forms are recognized such as porokeratosis of Mibelli (PM), linear porokeratosis, disseminated superficial actinic porokeratosis, punctate parakeratosis. PM should be treated because of the possibility of developing malignant epithelial tumors.
We are presenting a 21 year old male patient suffering from PM on the back of the hands, foot, scrotum, oral mucosa and anal region. The histological biopsy specimens showed the characteristic features of porokeratosis. We destroyed the lesions by cryotherapy sessions. Here, we present a case of PM since it is rarely seen as multiple lesions with oral, anal and scrotal involvements altogether.

Keywords: Multiple, analgenital involvement, porokeratozis Mibelli

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Farklý Porokeratoz formlarýnýn özelliklerini birarada gösteren ve anogenital bölgeyi de tutan bir olgu

Özlem Karabudak¹, Bilal Doðan¹, Aptullah Haholu², Yavuz Harmanyeri^1
1Gata Haydarpaþa Eðitim Hastanesi Deri ve Zührevi Hastalýklar Kliniði, Ýstanbul
²Gata Haydarpaþa Eðitim Hastanesi Patoloji Kliniði, Ýstanbul

Porokeratozis (PK), sýnýrýnda skuamýn olduðu, histopatolojik olarak ‘kornoid lamel’denilen parakeratotik keratinositlerin oluþturduðu sütunla karakterize bir grup keratinizasyon bozukluðudur (1). Klinik olarak porokeratozis Mibelli (PM), linear porokeratozis (LP), dissemine superfisial aktinik porokeratozis(DSAP), punktat porokeratozis (PP), palmoplantar porokeratozis(PPP) ve dev porokeratozis (DP) gibi formlarý bildirilmiþtir. Malign epitelial tümör geliþme riski nedeniyle tedavi edilmesi gerekir.
21 yaþýnda bir erkek hastayý el, ayak, skrotum, oral ve anal mukozadaki lezyonlarý nedeniyle sunmaktayýz. Biyopsilerin histopatolojik incelemesi, tipik porokeratozis özellikleri göstermekteydi. Lezyonlara kriyoterapi uygulandý.
Burada PM olgusunu çok sayýda lezyonun oral, anal, skrotal tutulumla birarada ender olarak görülmesi nedeniyle sunmaktayýz.

Anahtar Kelimeler: Multipl, anogenital tutulum, porokeratozis Mibelli

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