Turkderm-Turk Arch Dermatol Venereol. 2013; 47(4): 236-238 | DOI: 10.4274/turkderm.24445

Recurrent toxin-mediated perineal erythema: A case report and literature review

Sema Aytekin
S. B. Haydarpasa Numune Training And Research Hospital, Clinic Of Skin And Venereal Diseases, Istanbul, Turkey

Recurrent toxin-mediated perineal erythema (RTPE) is a benign self-limiting mucocutaneous disorder that caused super antigens produced by staphylococci and streptococci. It is characterized by generally asymptomatic well-emarginated desquamating erythema involving the perineum, groin or lower abdomen. Other typical features of illness such as acral edema, strawberry tongue and mucositis are often present. RTPE recover rapidly following antibiotic therapy. Herein we report 10-year-old boy with RTPE who presented strawberry tongue, recurrent desquamating perineal erythema. We also reviewed the literature on diseases that toxin mediated and/or with perineal erythema. Pediatric patients with exanthema are mostly seen primarily by pediatrician or family physician, are rarely also seen by dermatologist. With this report, we wish to alert the dermatologists.

Keywords: Perineal erythema, Recurrent toxin-mediated perineal erythema, Baboon syndrome, symmetrical drug-related intertriginous and flexural exanthema, SDRIFE

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Toksinlerle oluþan rekürren perineal eritem: Olgu sunumu ve literatür deðerlendirmesi

Sema Aytekin
S. B. Haydarpaþa Numune Eðitim Ve Araþtýrma Hastanesi, Deri Ve Zührevi Hastalýklar Kliniði, Ýstanbul, Türkiye

Toksinlerle oluþan rekürren perineal eritem (TORPE), stafilokok ve streptokok süperantijenleriyle oluþan, kendiliðinden iyileþen bir hastalýktýr. Ýnguinal bölge, perine veya alt abdomende yerleþen, genellikle asemptomatik, iyi sýnýrlý deskuamatif eritemle karakterizedir. Hastalýðýn diðer tipik özellikleri ise akral ödem, çilek dil ve mukozittir. TORPE, antibiyotik tedavisini izleyen günlerde hýzla iyileþir. Burada 10 yaþýnda, çilek dil ve rekürren deskuamatif perineal eritem bulunan TORPE li bir olgu sunulmaktadýr. Ayrýca toksinle oluþan ve/veya perineal eritem bulunan hastalýklar literatürde deðerlendirilmiþtir. Egzantemli pediatrik hastalar genellikle aile hekimleri veya pediatristler, nadiren de dermatologlar tarafýndan deðerlendirilir. Biz bu olguyla dermatologlarýn dikkatini çekmek istedik.

Anahtar Kelimeler: Perineal eritem, Recurrent toxin-mediated perineal erythema, Baboon sendromu, simetrik ilaçla iliþkili intertrijinöz ve fleksural egzantem, SDRIFE

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