A case of angioedema-like atypic scleromyxedema responding to treatment with steroid

Lichen myxedematosus is a chronic, inflammatory, systemic dermatose characterized by dermal musin deposition and increased fibroblasts in the absence of thyroid dysfunction. It is usually seen together with paraproteinemia. It is clinically classified as scleromyxedema (papular mucinosis), localized lichen myxedematosus, and atypical lichen myxedematosus. Etiopathogenesis of the disease which is very difficult to treat is still unknown. Herein, we present a case of atypical scleromyxedema without monoclonal gammopathy mimicking angioedema, rapidly developing and responding to steroid treatment.

Steroid tedavisine yanýt veren anjiyoödem benzeri atipik skleromiksödem olgusu

Liken miksödematoz, deride müsin birikimi ve fibroblast artýþýyla seyreden, tiroid bozukluklarýnýn eþlik etmediði kronik, sistemik, enflamatuvar bir dermatozdur. Genellikle paraproteinemiler ile birlikte görülür. Klinik olarak skleromiksödem (papüler müsinöz), lokalize liken miksödematozus, atipik liken miksödematozus olarak sýnýflandýrýlýr. Tedavisi oldukça güç olan hastalýðýn etiyopatogenezi halen tam anlaþýlamamýþtýr. Burada anjiyoödem benzeri baþlangýç gösterip, hýzlý geliþen ve steroid tedavisine cevap veren monoklonal gamopatisiz atipik bir skleromiksödem olgusu sunulacaktýr.