Topical use of GM-CSF for a nonhealing ulcer in a diabetic patient

Wound healing in diabetic patients is difficult and poor. Granulocyte macrophage colony stimulating factor (GM-CSF) is a cytokine that has been shown to stimulate wound healing. Recently, it has been successfully used for the treatment of ulcers caused by different factors. Here we report a diabetic patient whose traumatic leg ulcer did not show any improvement by local wound care but resolved rapidly after topical granulocyte macrophage colony stimulating factor application.

Diabetik bir hastada topikal GM-CSF'in yara tedavisinde kullanýmý

Diabetik hastalarda yara iyileþmesi yavaþlamaktadýr. Yara iyileþmesini uyarabilen bir sitokin olan granülosit makrofaj koloni stimüle edici faktör (GM-CSF), son yýllarda, farklý nedenlere baðlý ülserlerde baþarýyla kullanýlmaktadýr. Bu yazýda, lokal yara bakýmýna raðmen iyileþme göstermeyen travmatik bacak ülseri, topikal GM-CSF uygulamasý sonrasýnda hýzla düzelen diabetik bir hasta sunulmaktadýr.