Psoriasis üzerinde poliozis

Poliozis, hipopigmente veya depigmente kýllardan oluþan lokalize alaný tanýmlamak için kullanýlan bir terimdir. Bu tablonun foliküler melanositlerin inflamatuvar veya otoimmün bir mekanizmayla yýkýmý sonucu oluþtuðuna inanýlmaktadýr. Poliozis bazý herediter sendromlarla birlikte görülebileceði gibi inflamasyon, irradyasyon veya infeksiyonu takiben ve bazý ilaçlarla edinsel olarak da oluþabilir. Ayrýca bazý nevüsler, melanom ve nörofibrom gibi bazý benin ve malin lezyonlar üzerinde de geliþebileceði bildirilmiþtir. Ancak literatürde T hücre aracýlý otoimmün inflamatuvar bir hastalýk olan psoriasis ile poliozis iliþkisine dair bir veri bulunmamaktadýr. Burada saçlý derideki psoriasis plaðý üzerinde poliozis geliþen 11 yaþýnda bir kýz olgu sunulmaktadýr.

Poliosis overlying psoriasis

Poliosis is the term used to describe a localized area of hypopigmented or depigmented hairs. It is believed that this condition is a result of the destruction of follicular melanocytes by an inflammatory or autoimmune mechanism. Poliosis can occur in several hereditary syndromes or is acquired after inflammation, irradiation or infection and some medications. Additionally, it has also been reported that it can overlie some benign and malignant lesions, including some nevi, melanoma and neurofibroma. On the other hand, there has been no prior data of an association between psoriasis, which is a T-cell-mediated autoimmune inflammatory disease, and poliosis in the literature. Here, we describe an 11-year-old female with poliosis of the scalp overlying a plaque of psoriasis.